Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372785 | 0.96 | HRH3 (0.34) | HRH3GRIA1GRIA2GRIA3CYP2A6 | |
| SCHEMBL10479934 | 0.96 | HRH3 (0.34) | HRH3GRIA1GRIA2GRIA3CYP2A6 | |
| SCHEMBL8376587 | 0.93 | HRH3 (0.37) | HRH3GRIA1GRIA2GRIA3KDM1A | |
| SCHEMBL8857679 | 0.81 | CCR5 (0.39) | HSD17B10SLC6A2SLC6A4 | |
| SCHEMBL10968057 | 0.80 | KDM1A (0.37) | HRH3KDM1ATSHRHSD17B10MAOB | |
| SCHEMBL10932784 | 0.80 | HRH3 (0.34) | HRH3CYP2A6CYP19A1MAOAMAOB | |
| SCHEMBL10932772 | 0.80 | HRH3 (0.34) | HRH3CYP2A6CYP19A1MAOAMAOB | |
| SCHEMBL8483120 | 0.80 | GAA (0.39) | HRH3SIGMAR1 | |
| SCHEMBL1031530 | 0.80 | GAA (0.39) | HRH3SIGMAR1 | |
| SCHEMBL9348274 | 0.79 | FASN (0.38) | HRH3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394417-B1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0394417-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1990-10-31 | — | — | EP | disclosed |