Sulfamerazine

Sulfamerazine

SCHEMBL93591

Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1.[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Sulfamerazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.97
CYP2C9 P11712 1/20 0.97
NPSR1 Q6W5P4 1/20 0.71
ALDH1A1 P00352 2/20 0.68
CYP3A4 P08684 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
MAPK1 P28482 1/20 0.68
FASN P49327 1/20 0.65
LMNA P02545 2/20 0.65
AURKA O14965 1/20 0.65
DHFR P00374 1/20 0.65
TSHR P16473 1/20 0.65
KMT2A Q03164 1/20 0.61
RXFP1 Q9HBX9 2/20 0.58
POLB P06746 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamerazine SCHEMBL29538415 0.98 MAPT (1.00) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL33999 0.98 MAPT (1.00) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL5871007 0.97 MAPT (0.97) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL28028780 0.96 MAPT (0.94) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL8159446 0.94 MAPT (0.92) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamethazine SCHEMBL4231556 0.93 MAPT (0.89) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL28859835 0.93 MAPT (0.89) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL28086386 0.93 MAPT (0.89) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamethazine SCHEMBL30306297 0.90 MAPT (0.82) MAPTCYP2C9NPSR1ALDH1A1CYP3A4
Sulfamerazine SCHEMBL10619389 0.88 MAPT (0.81) MAPTCYP2C9NPSR1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59063147-A None JP disclosed
WO-2023120292-A1 LIGHT SULFONAMIDE SYNTHESIS REACTION 国立大学法人東京工業大学 2023-06-29 WO disclosed
US-9890238-B2 Curing catalyst for epoxy resin composition, epoxy resin composition comprising same, and apparatus manufactured by using same SAMSUNG SDI CO., LTD. (KR) 2018-02-13 US disclosed
CN-104407206-B A kind of pharmaceutical production detects warning circuit with agitated kettle 佛山市南海北沙制药有限公司 2017-03-29 CN disclosed
US-20160326303-A1 CURING CATALYST FOR EPOXY RESIN COMPOSITION, EPOXY RESIN COMPOSITION COMPRISING SAME, AND APPARATUS MANUFACTURED BY USING SAME SAMSUNG SDI CO., LTD. (KR) 2016-11-10 US disclosed
CN-101842012-B Eliminating fish parasites expellent and method for control of fish parasites NIPPON SUISAN Kabushiki Kaisha Ltd. (JP) 2016-04-27 CN disclosed
EP-2425857-B1 ANTIPARASITIC COMPOSITIONS FOR CONTROLLING THE PROLIFERATION OF FISH PARASITES NIPPON SUISAN KAISHA LTD (JP) 2016-04-20 EP disclosed
CN-204269723-U Pharmaceutical production agitated kettle detection alarm circuit NANHAI BEISHA PHARMACEUTICAL CO LTD 2015-04-15 CN disclosed
CN-104407206-A Stirring pot detection alarm circuit for pharmaceutical production NANHAI BEISHA PHARMACEUTICAL CO LTD 2015-03-11 CN disclosed
CN-102413841-A Method for control of fish parasites NIPPON SUISAN KAISHA LTD 2012-04-11 CN disclosed
CN-101842012-A Parasite control agent for fish, and parasite control method for fish NIPPON SUISAN KAISHA LTD 2010-09-22 CN disclosed
EP-2213169-A1 PARASITE CONTROL AGENT FOR FISH, AND PARASITE CONTROL METHOD FOR FISH Nippon Suisan Kaisha, Ltd. (JP) 2010-08-04 EP disclosed
EP-0485388-B1 VACCINE FOR IMMUNIZING CATS AGAINST TOXOPLASMA OOCYST SHEDDING UNIV KANSAS (US) 1997-09-10 EP disclosed
EP-0485388-A4 VACCINE FOR IMMUNIZING CATS AGAINST TOXOPLASMA OOCYST SHEDDING 1993-02-10 EP disclosed
EP-0485388-A1 VACCINE FOR IMMUNIZING CATS AGAINST TOXOPLASMA OOCYST SHEDDING. UNIV KANSAS (US) 1992-05-20 EP disclosed
US-5045313-A Toxoplasma gondii mutant THE UNIVERSITY OF KANSAS (US) 1991-09-03 US disclosed
WO-1991000740-A1 VACCINE FOR IMMUNIZING CATS AGAINST TOXOPLASMA OOCYST SHEDDING THE UNIVERSITY OF KANSAS (US) 1991-01-24 WO disclosed
US-4665100-A REDUCTION OF CARRYOVER TO SUBSEQUENT LOTS ELI LILLY AND COMPANY (US) 1987-05-12 US disclosed
JP-S5963147-A MODIFICATION OF PISCICULTURE FEED MARINE PROJECT:KK 1984-04-10 JP disclosed
EP-0060680-A1 Process for formulating a medicated animal feed premix ELI LILLY AND COMPANY (US) 1982-09-22 EP disclosed