Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 4/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359246 | 1.00 | ABCC9 (0.52) | ABCC9ABCB1 | |
| SCHEMBL9359250 | 1.00 | ABCC9 (0.52) | ABCC9ABCB1 | |
| SCHEMBL10886662 | 0.89 | ABCC9 (0.58) | ABCC9 | |
| SCHEMBL16027515 | 0.86 | ABCC9 (0.56) | ABCC9 | |
| SCHEMBL11391588 | 0.85 | ABCB1 (0.53) | ABCC9ABCB1 | |
| SCHEMBL11391593 | 0.85 | ABCB1 (0.53) | ABCC9ABCB1 | |
| SCHEMBL11391595 | 0.85 | ABCB1 (0.53) | ABCC9ABCB1 | |
| Hydrochloric Acid SCHEMBL11400067 | 0.84 | ABCB1 (0.52) | ABCC9ABCB1 | |
| Hydrochloric Acid SCHEMBL11400068 | 0.84 | ABCB1 (0.52) | ABCC9ABCB1 | |
| Hydrochloric Acid SCHEMBL11400062 | 0.84 | ABCB1 (0.52) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426379-B1 | Substituted cyclobutenedione compounds | BEECHAM GROUP PLC (GB) | 1994-12-21 | — | — | EP | disclosed |
| US-5147866-A | Hypotensive, bronchodilator agents | BEECHAM GROUP P.L.C. (GB) | 1992-09-15 | — | — | US | disclosed |
| EP-0426379-A2 | Substituted cyclobutenedione compounds | Beecham Group p.l.c. (GB) | 1991-05-08 | — | — | EP | disclosed |