Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356140 | 0.86 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL29369823 | 0.86 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL166668 | 0.85 | CYP3A4 (0.49) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL29812870 | 0.81 | CYP3A4 (0.40) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL241344 | 0.81 | CYP3A4 (0.51) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL1071989 | 0.81 | CYP3A4 (0.40) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL28377763 | 0.80 | CYP3A4 (0.45) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL11441057 | 0.80 | CYP3A4 (0.53) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL124245 | 0.77 | CYP3A4 (0.59) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL29510769 | 0.77 | CYP3A4 (0.59) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465302-B1 | Precursors of isocyanurate polymers having hydroxyl, urethane, isocyanate or acrylate groups, and process for their preparation | ATOCHEM ELF SA (FR) | 1994-12-28 | — | — | EP | disclosed |
| US-5256748-A | Michael condensation of isocyanuric acid and hydroxyacrylated compound | AUTOCHEM (FR) | 1993-10-26 | — | — | US | disclosed |
| EP-0465302-A1 | Precursors of isocyanurate polymers having hydroxyl, urethane, isocyanate or acrylate groups, and process for their preparation | ELF ATOCHEM S.A. (FR) | 1992-01-08 | — | — | EP | disclosed |
| US-4446300-A | DIELECTRICS, FORMING TRIS/2-HYDROXYETHYL/ISOCYANURATE IN SITU FROM CYANURIC ACID AND ETHYLENE CARBONATE | THE P. D. GEORGE COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4243788-A | UNSATURATED ISOCYANURATE, UNSATURATED SOLVENT | ICI AMERICAS INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4159376-A | IMPACT STRENGTH, CORROSION RESISTANCE, CARBAMYLATION | ICI AMERICAS INC. (US) | 1979-06-26 | — | — | US | disclosed |
| US-4145544-A | TRIMERIZING AROMATIC ISOCYANATE AND AN UNSATURATED SOLVENT, REACTING WITH ALCOHOL | ICI AMERICAS INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-3963681-A | POLYETHERURETHANE COPOLYMERS | BRIDGESTONE TIRE COMPANY LIMITED (JA) | 1976-06-15 | — | — | US | disclosed |