Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241344 | 0.90 | CYP3A4 (0.51) | CYP3A4TRPA1FURINTDP1MAPK1 | |
| SCHEMBL10906029 | 0.87 | CYP3A4 (0.45) | CYP3A4TRPA1FURINTDP1MAPK1 | |
| SCHEMBL9359283 | 0.85 | CYP3A4 (0.50) | CYP3A4TRPA1FURINTDP1MAPK1 | |
| SCHEMBL1191181 | 0.83 | CYP1A2 (0.53) | CYP3A4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL673041 | 0.81 | KMT2A (0.44) | CYP3A4TDP1MAPK1LMNAGAA | |
| SCHEMBL9359157 | 0.80 | CYP3A4 (0.49) | CYP3A4TRPA1FURINTDP1MAPK1 | |
| SCHEMBL1071989 | 0.80 | CYP3A4 (0.40) | CYP3A4TRPA1FURINTDP1MAPK1 | |
| SCHEMBL29812870 | 0.80 | CYP3A4 (0.40) | CYP3A4TRPA1FURINTDP1MAPK1 | |
| SCHEMBL9359042 | 0.80 | CYP3A4 (0.43) | CYP3A4TRPA1TDP1MAPK1TTR | |
| SCHEMBL9359064 | 0.79 | CYP3A4 (0.69) | CYP3A4TRPA1FURINTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 677 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369911-A1 | HYDROGEL COMPOSITIONS | UNIVERSITÉ DE HAUTE-ALSACE (FR) | 2021-12-02 | — | — | US | claimed |
| CN-108137780-B | Preparation of polyamideimides | 亨斯迈先进材料许可(瑞士)有限公司 | 2021-07-30 | — | — | CN | claimed |
| EP-3569625-A1 | POLYURETHANE HOTMELT ADHESIVE WHICH DO NOT CAUSE POLARIZER DISCOLORATION AT HTHH CONDITON | Henkel AG & Co. KGaA (DE) | 2019-11-20 | — | — | EP | claimed |
| US-9586446-B2 | Ballistic resilient run-flat tire, kit and method thereof | ACCELLA POLYURETHANE SYSTEMS LLC (US) | 2017-03-07 | — | — | US | claimed |
| US-20160361956-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ACCELLA POLYURETHANE SYSTEMS LLC | 2016-12-15 | — | — | US | claimed |
| EP-2819855-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | Arnco, Inc. (US) | 2015-01-07 | — | — | EP | claimed |
| WO-2013130113-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ARNCO (US) | 2013-09-06 | — | — | WO | claimed |
| US-20130220507-A1 | BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF | ARNCO (US) | 2013-08-29 | — | — | US | claimed |
| US-7101954-B2 | Polymeric urethane ester quats and their use in personal care compositions | ALZO INTERNATIONAL, INC. (US) | 2006-09-05 | — | — | US | claimed |
| US-7087700-B2 | Polymeric urethane ester tertiary amines and related personal care formulations | ALZO INTERNATIONAL, INC. (US) | 2006-08-08 | — | — | US | claimed |
| US-20040086482-A1 | Polymeric urethane ester tertiary amines and related personal care formulations | ZOFCHAK ALBERT (US) | 2004-05-06 | — | — | US | claimed |
| US-20030086950-A1 | Polymeric urethane ester quats and their use in personal care compositions | ALZO, INC. | 2003-05-08 | — | — | US | claimed |
| WO-2003016247-A2 | POLYMERIC URETHANE ESTER QUATS AND THEIR USE IN PERSONAL CARE COMPOSITIONS | ALZO INTERNATIONAL, INC. (US) | 2003-02-27 | — | — | WO | claimed |
| US-5352527-A | Having heat resistant protective layer containing amine-modified polysiloxane, polyisocyanate and reaction product between these | RICOH COMPANY, LTD. (JP) | 1994-10-04 | — | — | US | claimed |
| US-4618635-A | RADIATION CURABLE; HIGH TENSILE STRENGTH | UNION CARBIDE CORPORATION (US) | 1986-10-21 | — | — | US | claimed |
| US-4585702-A | CURED POLYMERIC BINDER COMPRISING LACTONE-ACRYLATE ADDUCT | UNION CARBIDE CORPORATION (US) | 1986-04-29 | — | — | US | claimed |
| EP-0133908-A2 | Compositions useful in curable coatings | UNION CARBIDE CORPORATION (US) | 1985-03-13 | — | — | EP | claimed |
| US-4321350-A | Process for the catalytic setting of polyurethane molding compositions | GAMBRO DIALYSATOREN KG (DE) | 1982-03-23 | — | — | US | claimed |
| US-4131693-A | Hardenable polyesterurethane composition for producing a directly tinnable wire | DR. BECK & CO AG (DE) | 1978-12-26 | — | — | US | claimed |
| US-3937673-A | DIELECTRICS | PHELPS DODGE INDUSTRIES, INC. (US) | 1976-02-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030086950-A1 | Polymeric urethane ester quats and their use in personal care compositions | HHAT, CUTA, DEK | CYP3A4 1843/4885TRPA1 448/4885FURIN 4178/4885 |
| US-20040086482-A1 | Polymeric urethane ester tertiary amines and related personal care formulations | BCKDK, DEK, ITK | CYP3A4 1643/4885TRPA1 161/4885FURIN 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.