Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 18/20 | 0.49 |
| ▸ | RARG | P13631 | 17/20 | 0.49 |
| ▸ | RARA | P10276 | 17/20 | 0.49 |
| ▸ | RXRA | P19793 | 6/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10834705 | 0.78 | RARB (0.59) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL4875804 | 0.74 | RARB (0.69) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10548537 | 0.73 | RARB (0.46) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10960163 | 0.73 | RARB (0.67) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL3838099 | 0.72 | RARB (0.57) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9747256 | 0.71 | RARB (0.71) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL5845704 | 0.71 | RARB (0.56) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8795360 | 0.70 | RARB (0.49) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL12168230 | 0.70 | RARB (0.69) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL3903148 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465343-B1 | Pharmaceutical or cosmetical composition comprising a retinoid and a sterol in association | CIRD GALDERMA (FR) | 1994-06-15 | — | — | EP | claimed |