SCHEMBL935979

SCHEMBL935979

O=C(c1ccccc1)c1cc(I)ccc1I

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 2/20 0.46
MEN1 O00255 2/20 0.46
USP2 O75604 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C8 P10632 1/20 0.46
CYP2C9 P11712 1/20 0.46
KDM4E B2RXH2 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
MAPT P10636 4/20 0.46
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.42
SRD5A2 P31213 1/20 0.42
PDE4A P27815 1/20 0.41
ITGA1 P56199 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL936088 0.85 SRD5A2 (0.54) AKR1C3MAPTPOLBMAPK1SRD5A2
SCHEMBL29980197 0.83 MAPT (0.64) AKR1C3ALDH1A1ATMTDP1L3MBTL1
SCHEMBL1877051 0.83 MAPT (0.64) AKR1C3ALDH1A1ATMTDP1L3MBTL1
SCHEMBL11641722 0.83 GAA (0.53) AKR1C3ALDH1A1ATMTDP1L3MBTL1
SCHEMBL20757754 0.83 AKR1C3 (0.62) AKR1C3ALDH1A1ATMTDP1L3MBTL1
SCHEMBL10994311 0.81 MAPT (0.57) ALDH1A1ATMGAAMEN1USP2
SCHEMBL27891589 0.81 MAPT (0.67) AKR1C3ALDH1A1MAPTPOLBMAPK1
SCHEMBL12671441 0.81 PTGS2 (0.51) AKR1C3ALDH1A1ATMTDP1L3MBTL1
SCHEMBL154090 0.79 AKR1C3 (0.61) AKR1C3ALDH1A1ATMTDP1L3MBTL1
SCHEMBL11351832 0.79 GAA (0.68) AKR1C3ALDH1A1ATMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471494-B star polymer Robert Bosch Ltd. (DE) 2015-11-25 CN claimed
US-9127129-B2 Star polymer ROBERT BOSCH GMBH (DE) 2015-09-08 US claimed
US-20120238699-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2012-09-20 US claimed
EP-2456812-A1 STAR POLYMER Robert Bosch GmbH (DE) 2012-05-30 EP claimed
WO-2011009949-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2011-01-27 WO claimed
CN-102471494-B star polymer Robert Bosch Ltd. (DE) 2015-11-25 CN disclosed
US-9127129-B2 Star polymer ROBERT BOSCH GMBH (DE) 2015-09-08 US disclosed
US-20120238699-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2012-09-20 US disclosed
EP-2456812-A1 STAR POLYMER Robert Bosch GmbH (DE) 2012-05-30 EP disclosed
WO-2011009949-A1 STAR POLYMER ROBERT BOSCH GMBH (DE) 2011-01-27 WO disclosed
US-20100105786-A1 Method for Producing Polymer Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-29 US disclosed
CN-1922236-A Method for producing polymer compound SUMITOMO CHEMICAL CO (JP) 2007-02-28 CN disclosed
EP-1721922-A1 METHOD FOR PRODUCING POLYMER COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238699-A1 STAR POLYMER STARD3, STARD10, STARD7 AKR1C3 2743/4885ALDH1A1 4777/4885ATM 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.