SCHEMBL936022

SCHEMBL936022

Nc1ncnc(-c2ccccn2)n1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.69
L3MBTL1 Q9Y468 5/20 0.69
ALOX15 P16050 4/20 0.69
TDP1 Q9NUW8 3/20 0.57
TP53 P04637 4/20 0.52
LMNA P02545 3/20 0.48
CCR1 P32246 2/20 0.48
CCR5 P51681 2/20 0.48
CCR8 P51685 2/20 0.48
METAP1 P53582 2/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
HTT P42858 4/20 0.47
ALPL P05186 2/20 0.47
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30818137 1.00 KDM4E (0.69) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL3616834 0.86 KDM4E (0.77) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL12176987 0.82 KDM4E (0.51) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL4331114 0.82 KDM4E (0.92) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL29913760 0.82 KDM4E (1.00) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL3345877 0.82 KDM4E (1.00) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL18895753 0.78 KDM4E (0.59) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL18905446 0.77 KDM4E (0.63) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL5846342 0.77 KDM4E (0.57) KDM4EL3MBTL1ALOX15TDP1TP53
SCHEMBL27463611 0.77 KDM4E (0.57) KDM4EL3MBTL1ALOX15TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185330-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-08-16 EP disclosed
EP-3663283-B1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THIN FILM FORMED FROM THE COMPOSITION SAMSUNG DISPLAY CO LTD (KR) 2021-11-03 EP disclosed
EP-3444860-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-02-20 EP disclosed
EP-3301097-A2 [1]BENZOTHIENO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) Samsung Display Co., Ltd. (KR) 2018-04-04 EP disclosed
EP-3229290-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-10-11 EP disclosed
EP-3185328-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP disclosed
EP-3185330-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP disclosed
EP-2694501-A1 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2014-02-12 EP disclosed
WO-2012130902-A1 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-10-04 WO disclosed
EP-2456766-A1 COMPOUNDS SUITABLE FOR USE AS ACTINIDE LIGANDS, SYNTHESIS AND USES THEREOF Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2012-05-30 EP disclosed
WO-2011009814-A1 COMPOUNDS SUITABLE FOR USE AS ACTINIDE LIGANDS, SYNTHESIS AND USES THEREOF Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2011-01-27 WO disclosed
EP-1218360-B1 TRIAZINE KINASE INHIBITORS AMGEN INC (US) 2008-05-28 EP disclosed
US-7074789-B2 Kinase inhibitors AMGEN INC. (US) 2006-07-11 US disclosed
US-20040116388-A1 triazine compoound inhibitors of enzymes that catalyze phosphoryl transfer and/or that bind ATP/GTP nucleotides AMGEN INC. 2004-06-17 US disclosed
EP-1218360-A1 TRIAZINE KINASE INHIBITORS Amgen Inc., (US) 2002-07-03 EP disclosed
WO-2001025220-A1 TRIAZINE KINASE INHIBITORS AMGEN INC. (US) 2001-04-12 WO disclosed