Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.92 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.92 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | CCR8 | P51685 | 2/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | ALPL | P05186 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913760 | 0.96 | KDM4E (1.00) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL3345877 | 0.96 | KDM4E (1.00) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL19445116 | 0.91 | KDM4E (0.76) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL29354466 | 0.89 | KDM4E (1.00) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL322756 | 0.89 | KDM4E (1.00) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL1704624 | 0.87 | KDM4E (0.76) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL789163 | 0.86 | KDM4E (0.95) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL29171375 | 0.86 | KDM4E (0.95) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL11213260 | 0.86 | KDM4E (0.95) | KDM4EL3MBTL1ALOX15TDP1TP53 | |
| SCHEMBL32681187 | 0.86 | KDM4E (0.95) | KDM4EL3MBTL1ALOX15TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160225472-A1 | POLYMERIC CHELATORS FOR METAL ION EXTRACTION AND SEPARATION | UNIV TEXAS (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160225471-A1 | FUNCTIONAL CONDUCTING POLYMERS FOR REDOX MEDIATED SEPARATIONS OF F-ELEMENTS | UNIV TEXAS (US) | 2016-08-04 | — | — | US | disclosed |
| US-9074266-B2 | 2,9-dipyridyl-1,10-phenanthroline derivatives useful as actinide ligands, method for synthesizing same, and uses thereof | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2015-07-07 | — | — | US | disclosed |
| WO-2015076911-A2 | FUNCTIONAL CONDUCTING POLYMERS FOR REDOX MEDIATED SEPARATIONS OF F-ELEMENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-28 | — | — | WO | disclosed |
| EP-2694501-B1 | 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-12-17 | — | — | EP | disclosed |
| US-8709129-B2 | Compounds useful as ligands of actinides, their synthesis and their uses | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-04-29 | — | — | US | disclosed |
| US-20140030172-A1 | 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF | UNIVERSITE DE NANTES (FR) | 2014-01-30 | — | — | US | disclosed |
| EP-2456766-B1 | COMPOUNDS SUITABLE FOR USE AS ACTINIDE LIGANDS, SYNTHESIS AND USES THEREOF | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2013-11-06 | — | — | EP | disclosed |
| US-20120186396-A1 | COMPOUNDS USEFUL AS LIGANDS OF ACTINIDES, THEIR SYNTHESIS AND THEIR USES | UNIVERSITE DE NANTES (FR) | 2012-07-26 | — | — | US | disclosed |
| US-7612010-B2 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7138363-B2 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-11-21 | — | — | US | disclosed |
| EP-1703977-A1 | USE OF A COMPOSITION COMPRISING METAL COMPLEX COMPOUNDS AND POLYPHOSPHONATES AS CATALYSTS FOR OXIDATIONS | Ciba SC Holding AG (CH) | 2006-09-27 | — | — | EP | disclosed |
| EP-1703976-A2 | USE OF METAL COMPLEX COMPOUNDS COMPRISING PYRIDINE, PYRIMIDINE OR S-TRIAZINE DERIVED LIGANDS AS CATALYSTS FOR OXIDATIONS WITH ORGANIC PEROXY ACIDS AND/OR PRECURSORS OF ORGANIC PEROXY ACIDS AND H2O2 | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-09-27 | — | — | EP | disclosed |
| EP-1556467-B1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA SC HOLDING AG (CH) | 2006-07-05 | — | — | EP | disclosed |
| US-20060052265-A1 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORP. | 2006-03-09 | — | — | US | disclosed |
| WO-2005105303-A1 | USE OF METAL COMPLEXES HAVING BISPYRIDYLPYRIMIDINE OR BISPYRIDYLTRIAZINE LIGANDS AS CATALYSTS FOR REACTIONS WITH PEROXY COMPOUNDS FOR BLEACHING COLOURED STAINS ON HARD SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005068075-A1 | USE OF A COMPOSITION COMPRISING METAL COMPLEX COMPOUNDS AND POLYPHOSPHONATES AS CATALYSTS FOR OXIDATIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-07-28 | — | — | WO | disclosed |
| WO-2005068074-A2 | USE OF METAL COMPLEX COMPOUNDS COMPRISING PYRIDINE PRYIMIDINE OR S-TRIAZNE DERIVED LIGANDS AS CATALYSTS FOR OXIDATIONS WITH ORGANIC PEROXY ACIDS AND/OR PRECURSORS OF ORGANIC PEROXY ACID AND H2O2 | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-07-28 | — | — | WO | disclosed |
| EP-1556467-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | Ciba SC Holding AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039934-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120186396-A1 | COMPOUNDS USEFUL AS LIGANDS OF ACTINIDES, THEIR SYNTHESIS AND THEIR USES | AHR, ARNT, HRH3 | KDM4E 4809/4885L3MBTL1 1174/4885ALOX15 204/4885 |
| US-20140030172-A1 | 2,9-DIPYRIDYL-1,10-PHENANTHROLINE DERIVATIVES USEFUL AS ACTINIDE LIGANDS, METHOD FOR SYNTHESIZING SAME, AND USES THEREOF | NRP1, AHR, NR0B1 | KDM4E 3994/4885L3MBTL1 4468/4885ALOX15 4432/4885 |
| US-20060052265-A1 | Use of metal complex compounds as oxidation catalysts | AP1M1, MLX, SOD1 | KDM4E 2650/4885L3MBTL1 630/4885ALOX15 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.