Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.61 |
| ▸ | AKT1 | P31749 | 2/20 | 0.61 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360691 | 0.86 | PDPK1 (0.56) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL20265727 | 0.83 | PDPK1 (0.54) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL11867406 | 0.83 | PDPK1 (0.54) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL9762855 | 0.82 | MAPT (0.53) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL9359744 | 0.82 | PDPK1 (0.53) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL9762934 | 0.82 | PDPK1 (0.53) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL18152701 | 0.81 | PDPK1 (0.52) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL1028879 | 0.81 | KMT2A (0.62) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL1028878 | 0.81 | KMT2A (0.62) | PDPK1AKT1CYTH3GPR35ALDH1A1 | |
| SCHEMBL4800113 | 0.80 | GPR35 (0.59) | PDPK1AKT1CYTH3GPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376047-B1 | 2-Amino-6-chloro-4-nitrophenol derivatives, process for their preparation and hair dyeing agent containing the same | WELLA AG (DE) | 1994-05-04 | — | — | EP | claimed |
| EP-0376047-B1 | 2-Amino-6-chloro-4-nitrophenol derivatives, process for their preparation and hair dyeing agent containing the same | WELLA AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0376047-A1 | 2-Amino-6-chloro-4-nitrophenol derivatives, process for their preparation and hair dyeing agent containing the same | Wella Aktiengesellschaft (DE) | 1990-07-04 | — | — | EP | disclosed |