Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16159994 | 0.93 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8982465 | 0.88 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9324299 | 0.86 | THRB (0.43) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL26487463 | 0.86 | TSHR (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL27707440 | 0.84 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12860141 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1250799 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9324315 | 0.81 | THRB (0.39) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2123596 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9765971 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394787-B1 | Compositions containing carbamide group containing (meth)acrylic acid esters for use as adhesive components for the treatment of collagenic materials in medicine, and preparation of the compositions | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| US-5300537-A | Bonding dental fillings | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0394787-A2 | Compositions containing carbamide group containing (meth)acrylic acid esters for use as adhesive components for the treatment of collagenic materials in medicine, and preparation of the compositions | BAYER AG (DE) | 1990-10-31 | — | — | EP | disclosed |