Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752213 | 0.99 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL9365276 | 0.99 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL7751226 | 0.88 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL9360601 | 0.88 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL9364857 | 0.87 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL7752204 | 0.87 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL7751238 | 0.87 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL7751505 | 0.87 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL7751498 | 0.87 | CYSLTR1 (0.52) | CYSLTR2CYSLTR1ALOX5APGPBAR1ADAMTS4 | |
| SCHEMBL9360073 | 0.83 | CYSLTR1 (0.51) | CYSLTR2CYSLTR1ALOX5APGPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399291-B1 | Substituted (Quinoline-2-yl-methoxy)phenyl-acyl-sulphonamides and cyanamides , process for their preparation and their use in medicines | BAYER AG (DE) | 1994-07-20 | — | — | EP | disclosed |