Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | GSK3B | P49841 | 8/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804436 | 0.90 | GSK3B (0.47) | PTGS2GSK3BPTPN1PDE4BSTK10 | |
| SCHEMBL2837669 | 0.87 | PTPN1 (0.58) | PTGS2GSK3BPTPN1 | |
| SCHEMBL211025 | 0.79 | PDE4B (0.59) | PTGS2GSK3BPDE4BALDH1A1STK10 | |
| SCHEMBL27825209 | 0.78 | GSK3B (0.42) | PTGS2GSK3B | |
| SCHEMBL9436192 | 0.78 | GSK3B (0.42) | PTGS2GSK3BALDH1A1 | |
| SCHEMBL3719735 | 0.78 | PTGS2 (0.51) | PTGS2GSK3BPDE4B | |
| SCHEMBL114611 | 0.76 | PTGS2 (0.67) | PTGS2GSK3BPDE4B | |
| SCHEMBL94149 | 0.75 | GSK3B (0.58) | PTGS2GSK3BPDE4B | |
| SCHEMBL15349924 | 0.74 | TDP1 (0.50) | PTGS2GSK3BALDH1A1 | |
| SCHEMBL5434280 | 0.74 | GSK3B (0.52) | PTGS2GSK3BSLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |