Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360648 | 0.86 | CYSLTR2 (0.49) | HDAC1HDAC8CYSLTR2CYSLTR1 | |
| SCHEMBL9721114 | 0.84 | HDAC1 (0.43) | HDAC1HDAC8TAAR1HTR2BMEN1 | |
| SCHEMBL9356843 | 0.84 | BID (0.49) | HDAC1CYSLTR2CYSLTR1 | |
| SCHEMBL9356850 | 0.84 | BID (0.49) | HDAC1CYSLTR2CYSLTR1 | |
| SCHEMBL9356490 | 0.84 | BID (0.49) | HDAC1CYSLTR2CYSLTR1 | |
| SCHEMBL10445309 | 0.84 | BID (0.49) | HDAC1CYSLTR2CYSLTR1 | |
| SCHEMBL9356495 | 0.84 | BID (0.49) | HDAC1CYSLTR2CYSLTR1 | |
| SCHEMBL9360569 | 0.82 | HDAC1 (0.45) | HDAC1HDAC8NR3C2MEN1KMT2A | |
| SCHEMBL9479613 | 0.81 | HDAC1 (0.41) | HDAC1HDAC8HTR2BMEN1KMT2A | |
| SCHEMBL9356520 | 0.81 | HDAC1 (0.39) | HDAC1HDAC8HTR2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403250-B1 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0403250-A2 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |