Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 10/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.56 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483749 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356485 | 0.84 | ALDH1A1 (0.73) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356798 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356781 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356904 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356883 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356806 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL9356895 | 0.73 | MAPT (0.66) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL2621729 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HTTTDP1MAPTL3MBTL1 | |
| SCHEMBL11803328 | 0.72 | HTT (0.59) | ALDH1A1HTTTDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285089-B1 | 4-Thioquinazoline derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4829069-A | 4-Thioquinazoline derivatives as antiulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0285089-A2 | 4-Thioquinazoline derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |