Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445228 | 1.00 | KMT2A (0.43) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL9360678 | 1.00 | KMT2A (0.43) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL9480268 | 0.85 | CETP (0.45) | KMT2AALDH1A1L3MBTL1TSHRFABP7 | |
| SCHEMBL9357231 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL9480264 | 0.85 | CETP (0.45) | KMT2AALDH1A1L3MBTL1TSHRFABP7 | |
| SCHEMBL8923595 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL9356797 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL9184980 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT | |
| SCHEMBL10446368 | 0.85 | CETP (0.45) | KMT2AALDH1A1L3MBTL1TSHRFABP7 | |
| SCHEMBL9356522 | 0.83 | L3MBTL1 (0.39) | KMT2AALDH1A1HSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403250-B1 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | disclosed |