SCHEMBL9360719

SCHEMBL9360719

Cc1cc(C(=O)O)c(C(=O)c2cccc3ccccc23)cc1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.70
NR4A1 P22736 1/20 0.62
NR4A2 P43354 1/20 0.62
NR4A3 Q92570 1/20 0.62
ALDH1A1 P00352 2/20 0.55
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
BCL2L1 Q07817 1/20 0.49
CNR2 P34972 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CNR1 P21554 1/20 0.48
PRNP P04156 1/20 0.47
PLK1 P53350 1/20 0.47
IGFBP3 P17936 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6051351 0.83 CDC25B (1.00) CDC25BNR4A1NR4A2NR4A3ALDH1A1
SCHEMBL8785629 0.81 ALDH1A1 (0.64) CDC25BALDH1A1KMT2AMEN1TDP1
SCHEMBL7915709 0.81 CDC25B (0.65) CDC25BNR4A1NR4A2NR4A3ALDH1A1
SCHEMBL7543580 0.81 CDC25B (0.82) CDC25BNR4A1NR4A2NR4A3KMT2A
SCHEMBL244802 0.80 CDC25B (0.80) CDC25BNR4A1NR4A2NR4A3KMT2A
SCHEMBL29414437 0.80 CDC25B (0.80) CDC25BNR4A1NR4A2NR4A3KMT2A
Naphthoic Acid SCHEMBL28197386 0.80 NR4A1 (0.78) CDC25BNR4A1NR4A2NR4A3ALDH1A1
SCHEMBL7190371 0.79 CDC25B (0.73) CDC25BNR4A1NR4A2NR4A3KMT2A
SCHEMBL7185612 0.79 CDC25B (0.73) CDC25BNR4A1NR4A2NR4A3KMT2A
SCHEMBL14124719 0.79 CDC25B (0.50) CDC25BNR4A1NR4A2NR4A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0407808-B1 Catalyst, process for preparation of same, and process for polymerization of olefins using same SHOWA DENKO KK (JP) 1994-12-07 EP disclosed
US-5208302-A Coordination Catalysts Containing a Ketoester, Stereoregular SHOWA DENKO K.K. (JP) 1993-05-04 US disclosed
US-5049533-A Titanium, magnesium, halogen, keto-ester 7 SHOWA DENKO K.K. (JP) 1991-09-17 US disclosed
EP-0407808-A2 Catalyst, process for preparation of same, and process for polymerization of olefins using same SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-01-16 EP disclosed