Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365698 | 0.84 | PTGER4 (0.44) | SMN1; SMN2PTGER4HPGDHTR1AMAPT | |
| SCHEMBL14027447 | 0.82 | IDO1 (0.45) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HTR1A | |
| SCHEMBL9361414 | 0.80 | UTS2R (0.40) | SMN1; SMN2UTS2RHPGDMAPTALDH1A1 | |
| SCHEMBL14303377 | 0.80 | UTS2R (0.44) | CYP1A2CYP2C9CYP2C19UTS2RHPGD | |
| SCHEMBL8283662 | 0.79 | CYP3A4 (0.43) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL20810715 | 0.78 | HDAC6 (0.52) | CYP1A2CYP2C9CYP2C19SMN1; SMN2PTGER4 | |
| SCHEMBL13274160 | 0.75 | PTGER4 (0.41) | CYP1A2CYP2C9CYP2C19SMN1; SMN2PTGER4 | |
| SCHEMBL8466778 | 0.72 | KMT2A (0.44) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9360746 | 0.72 | UTS2R (0.34) | CYP1A2CYP2C9CYP2C19UTS2RHTR1A | |
| SCHEMBL14003067 | 0.71 | SMN1; SMN2 (0.36) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |