Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | VCP | P55072 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365685 | 0.89 | ADRA1D (0.35) | UTS2RHTTHDAC1HTR1AADRA1D | |
| SCHEMBL9365717 | 0.85 | HDAC1 (0.40) | UTS2RVCPHDAC1ADRA1ATP53 | |
| SCHEMBL9013449 | 0.77 | UTS2R (0.33) | UTS2RVCPHTR1AADRA1DADRA1A | |
| SCHEMBL9362106 | 0.74 | HDAC1 (0.43) | UTS2RHDAC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9361359 | 0.72 | HDAC1 (0.40) | UTS2RHTTHDAC1GAATP53 | |
| SCHEMBL9360834 | 0.72 | CYP1A2 (0.40) | UTS2RHTR1APDE3BPDE3ACYP1A2 | |
| SCHEMBL9012295 | 0.70 | TXN (0.35) | HTTHDAC1GAACYP1A2CYP2E1 | |
| SCHEMBL9329023 | 0.70 | VCP (0.32) | UTS2RVCPHTR1AADRA1DADRA1A | |
| SCHEMBL9361383 | 0.70 | HDAC1 (0.42) | UTS2RHTTHDAC1PDE3A | |
| SCHEMBL9011939 | 0.69 | HDAC1 (0.45) | HDAC1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |