Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 18/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001502 | 0.78 | MME (0.37) | MMEUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27590820 | 0.78 | MME (0.49) | CYP2C19MME | |
| SCHEMBL4001628 | 0.77 | MME (0.36) | MMEUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL9341047 | 0.77 | CYP2C19 (0.36) | CYP2C19MME | |
| SCHEMBL7368344 | 0.77 | CYP2C19 (0.36) | CYP2C19MME | |
| SCHEMBL9337097 | 0.77 | CYP2C19 (0.36) | CYP2C19MME | |
| SCHEMBL3998168 | 0.76 | USP2 (0.39) | MMEUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL7296981 | 0.76 | CYP2C19 (0.35) | CYP2C19MME | |
| SCHEMBL4001005 | 0.74 | TSHR (0.35) | CYP2C19MMETSHR | |
| SCHEMBL3999952 | 0.74 | USP2 (0.42) | MMEUSP2ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432898-B1 | Glutaric acid derivatives and preparation thereof | PFIZER LTD (GB) | 1994-04-13 | — | — | EP | disclosed |
| US-5260467-A | Glutaric acid derivatives and preparation thereof | PFIZER INC. (US) | 1993-11-09 | — | — | US | disclosed |
| US-5157138-A | Glutaric acid derivatives and preparation thereof | PFIZER, INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5087732-A | GLUTARIC ACID DERIVATIVES AND PREPARATION THEREOF | PFIZER INC. (US) | 1992-02-11 | — | — | US | disclosed |
| EP-0432898-A2 | Glutaric acid derivatives and preparation thereof | Pfizer Limited (GB) | 1991-06-19 | — | — | EP | disclosed |