Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361457 | 1.00 | ACAT1 (0.67) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9362439 | 0.96 | ACAT1 (0.73) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9361404 | 0.96 | ACAT1 (0.70) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9365181 | 0.96 | ACAT1 (0.73) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9362298 | 0.96 | ACAT1 (0.73) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9365091 | 0.96 | ACAT1 (0.70) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9361811 | 0.95 | ACAT1 (0.66) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9362330 | 0.95 | ACAT1 (0.66) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9365138 | 0.95 | ACAT1 (0.66) | ACAT1HDAC1HDAC8HDAC6SMPD1 | |
| SCHEMBL9361174 | 0.95 | ACAT1 (0.71) | ACAT1HDAC1HDAC8HDAC6SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424194-B1 | Benzanilide derivatives and their use as anti-atherosclerotic agents | RHONE POULENC SANTE (FR) | 1994-08-31 | — | — | EP | disclosed |
| US-5159114-A | Anticholesterol agents | RHONE-POULENC SANTE (FR) | 1992-10-27 | — | — | US | disclosed |
| EP-0424194-A2 | Benzanilide derivatives and their use as anti-atherosclerotic agents | RHONE-POULENC SANTE (FR) | 1991-04-24 | — | — | EP | disclosed |