Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | MC4R | P32245 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HRH1 | P35367 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | SCN1A | P35498 | 1/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19498788 | 1.00 | SIGMAR1 (1.00) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL19505657 | 0.90 | SIGMAR1 (0.83) | SIGMAR1OPRK1 | |
| SCHEMBL19505482 | 0.90 | SIGMAR1 (0.81) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL19505654 | 0.90 | SIGMAR1 (0.83) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL19505615 | 0.90 | SIGMAR1 (0.81) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL19505613 | 0.90 | SIGMAR1 (0.83) | SIGMAR1OPRK1 | |
| SCHEMBL29059547 | 0.90 | SIGMAR1 (0.81) | SIGMAR1ADRB2ADRB1HTR1AADORA3 | |
| SCHEMBL22043230 | 0.89 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL13589884 | 0.89 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL18645287 | 0.89 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | disclosed |