Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877398 | 0.81 | TSHR (0.53) | LMNAL3MBTL1MAPK1CNR2ALDH1A1 | |
| SCHEMBL11503163 | 0.72 | LMNA (0.69) | LMNAL3MBTL1MAPK1ALDH1A1TSHR | |
| SCHEMBL13855345 | 0.71 | ATM (0.52) | LMNAL3MBTL1CNR2ALDH1A1TDP1 | |
| SCHEMBL1419881 | 0.70 | CYP1A2 (0.55) | LMNAL3MBTL1ALDH1A1TSHRKMT2A | |
| Dibutylsuccinate SCHEMBL27980859 | 0.70 | PPARA (0.54) | LMNAL3MBTL1MAPK1ELANEALDH1A1 | |
| SCHEMBL50280 | 0.69 | GAA (0.72) | LMNAL3MBTL1MAPK1ELANETSHR | |
| SCHEMBL16352944 | 0.69 | CHRM2 (0.49) | LMNAL3MBTL1MAPK1TSHRTDP1 | |
| SCHEMBL21861229 | 0.69 | HDAC3 (0.40) | LMNAALDH1A1TSHRTDP1PPARG | |
| Benzophenone SCHEMBL29265024 | 0.69 | ELANE (0.54) | LMNAL3MBTL1MAPK1ELANEALDH1A1 | |
| SCHEMBL9880795 | 0.69 | TSHR (0.46) | LMNATSHRTDP1PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407808-B1 | Catalyst, process for preparation of same, and process for polymerization of olefins using same | SHOWA DENKO KK (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5208302-A | Coordination Catalysts Containing a Ketoester, Stereoregular | SHOWA DENKO K.K. (JP) | 1993-05-04 | — | — | US | disclosed |
| US-5049533-A | Titanium, magnesium, halogen, keto-ester 7 | SHOWA DENKO K.K. (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0407808-A2 | Catalyst, process for preparation of same, and process for polymerization of olefins using same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-01-16 | — | — | EP | disclosed |