Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150335 | 0.87 | TSHR (0.55) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| SCHEMBL250199 | 0.87 | ALDH1A1 (0.55) | TDP1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL29664068 | 0.87 | TSHR (0.55) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| SCHEMBL8607533 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| SCHEMBL6678754 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| Potassium SCHEMBL999033 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| SCHEMBL6552111 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| SCHEMBL2291963 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| SCHEMBL2972939 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC | |
| Hydrochloric Acid SCHEMBL627715 | 0.84 | TSHR (0.52) | TDP1ALDH1A1TSHRSMN1; SMN2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100361992-C | Sulfonamide substituted xanthine derivatives for use as PEPCK inhibitors | HOFFMANN LA ROCHE (CH) | 2008-01-16 | — | — | CN | disclosed |
| CN-1751044-A | Sulfonamide substituted xanthine derivatives for use as PEPCK inhibitors | HOFFMANN LA ROCHE (CH) | 2006-03-22 | — | — | CN | disclosed |
| EP-0214853-B1 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING & MFG (US) | 1994-11-30 | — | — | EP | disclosed |
| US-4883864-A | COUPLED AND FREE AMINE GROUPS CAPPED WITH UREA OR AMIDE GROUPS, EYE SURGERY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4851513-A | Viscoelastic collagen solution for opthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4713446-A | COLLAGEN COUPLED TO CARBONYL OR SULFONYL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0214853-A2 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |