Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364766 | 0.77 | MAPK1 (0.50) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9365480 | 0.73 | AKR1B1 (0.38) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL9361507 | 0.71 | MAPK1 (0.46) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9365438 | 0.71 | MAPK1 (0.46) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9876858 | 0.70 | MAPK1 (0.58) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8676657 | 0.69 | MAPK1 (0.60) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL5212814 | 0.67 | MAPK1 (0.71) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10596845 | 0.67 | MAPK1 (0.57) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10821313 | 0.66 | MAPK1 (0.44) | MAPK1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL6313351 | 0.63 | MPL (0.47) | MAPK1KDM4EALDH1A1HSD17B10PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5061794-A | Effective against pseudomonads | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241901-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-10-21 | — | — | EP | disclosed |