SCHEMBL5212814

SCHEMBL5212814

CC(=O)Oc1cccc(OC(C)=O)c1OC(C)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.71
▸ PTPN1 P18031 1/20 0.56
▸ KDM4E B2RXH2 4/20 0.55
▸ ALDH1A1 P00352 3/20 0.55
▸ HSD17B10 Q99714 3/20 0.55
▸ PTGS2 P35354 3/20 0.55
▸ BLM P54132 2/20 0.55
▸ TDP1 Q9NUW8 2/20 0.55
▸ HPGD P15428 2/20 0.55
▸ ESR1 P03372 1/20 0.55
▸ ITGB3 P05106 1/20 0.55
▸ ITGA2B P08514 1/20 0.55
▸ HMGB1 P09429 1/20 0.55
▸ TSHR P16473 1/20 0.55
▸ GGT1 P19440 1/20 0.55
▸ PTGS1 P23219 1/20 0.55
▸ NAPRT Q6XQN6 1/20 0.55
▸ TOP1 P11387 3/20 0.54
▸ POLB P06746 1/20 0.54
▸ GAA P10253 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875254 0.92 MAPK1 (0.62) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL1143040 0.87 PTPN1 (0.68) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL29940577 0.87 PTPN1 (0.68) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL29350633 0.87 MAPK1 (0.62) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL10808312 0.87 MAPK1 (0.62) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL15165086 0.87 MAPK1 (0.57) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL3755885 0.86 MAPK1 (0.56) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL6937651 0.86 MAPK1 (0.61) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL10351036 0.86 MAPK1 (0.61) MAPK1PTPN1KDM4EALDH1A1HSD17B10
SCHEMBL702527 0.86 MAPK1 (0.61) MAPK1PTPN1KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304842-A2 Isoprenoid derivatives and anti-ulcer agents containing the same NISSHIN FLOUR MILLING CO., LTD. (JP) 1989-03-01 — — EP claimed
JP-3128925-A — — None — — JP disclosed
CN-119455909-A Sulfonate post-modified conjugated microporous polymer cesium adsorbent and preparation method thereof 国能神东煤炭集团有限责任公司 2025-02-18 — — CN disclosed
US-20240245784-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION (US) 2024-07-25 — — US disclosed
EP-3614113-B1 TEMPERATURE DETECTING MATERIAL AND PRODUCT CONTROL METHOD HITACHI INDUSTRY EQUIPMENT SYSTEMS CO LTD (JP) 2024-07-17 — — EP disclosed
US-11933677-B2 Temperature detecting material, temperature detecting ink using same, temperature indicator, and product control system HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2024-03-19 — — US disclosed
EP-3614113-A1 TEMPERATURE DETECTION MATERIAL, TEMPERATURE DETECTION INK USING SAME, TEMPERATURE INDICATOR, AND ARTICLE MANAGEMENT SYSTEM HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2020-02-26 — — EP disclosed
US-20200041359-A1 Temperature Detecting Material, Temperature Detecting Ink Using Same, Temperature Indicator, and Product Control System HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) 2020-02-06 — — US disclosed
EP-3529356-A1 CONCERTED PROCESSES FOR FORMING 1,2,4-TRIHYDROXYBENZENE FROM HYDROQUINONE Lockheed Martin Energy, LLC (US) 2019-08-28 — — EP disclosed
EP-2709977-B1 USE OF BENZOTROPOLONE DERIVATIVES AS PHOTOSTABILIZER AND ANTIOXIDANT FOR STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS. BASF SE (DE) 2018-09-05 — — EP disclosed
EP-0033423-B1 ANISOTROPIC MELT-FORMING POLYMER IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-09-10 — — EP disclosed
US-4542203-A Method for producing branched aromatic polyesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-17 — — US disclosed
US-4417043-A CROSS LINKING RESIDUES GIVE POLYMER INVERSE SHEAR DEPENDENT VISCOSITY IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-22 — — US disclosed
US-4410683-A FROM HYDROXY-ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-18 — — US disclosed
EP-0083426-A1 Aromatic, melt-processible (co)polyesters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-13 — — EP disclosed
EP-0013085-B1 PROCESS FOR PREPARING PYROGALLOL FBC LIMITED (GB) 1983-02-16 — — EP disclosed
EP-0033423-A2 Anisotropic melt-forming polymer IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-08-12 — — EP disclosed
US-4275247-A DEOXIMATING CYCLOHEXANE-1,2,3-TRIONE OXIME BY HYDROLYSIS TO FORM PYROGALLOL FISONS LIMITED (GB) 1981-06-23 — — US disclosed
EP-0013085-A1 Process for preparing pyrogallol FBC LIMITED (GB) 1980-07-09 — — EP disclosed
US-3932506-A FOR HYDROLYSIS OF ACRYLONITRILE TO ACRYLAMIDE NALCO CHEMICAL COMPANY (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245784-A1 TARGETED NUCLEIC ACID CONJUGATE COMPOSITIONS HAVCR2, DCTD, POLRMT MAPK1 4499/4885PTPN1 4148/4885KDM4E 4319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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