Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361562 | 1.00 | CA1 (0.55) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL8076235 | 1.00 | CA1 (0.55) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL9365144 | 0.94 | DRD2 (0.61) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL9361443 | 0.94 | DRD2 (0.61) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL8603749 | 0.87 | CA1 (0.56) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL8074259 | 0.87 | CA1 (0.56) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL970670 | 0.87 | CA1 (0.56) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL345517 | 0.87 | CA1 (0.56) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL8066286 | 0.85 | CA1 (0.59) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL8603697 | 0.85 | CA1 (0.59) | CA1CA2ACHEDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436435-B1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | SANOFI ELF (FR) | 1994-03-23 | — | — | EP | disclosed |
| US-5130339-A | Intestine and uterine motility modulators for reduction of intraocular pressure for glaucoma treatment | SANOFI (FR) | 1992-07-14 | — | — | US | disclosed |
| EP-0436435-A1 | Phenylethanolaminomethyltetralins, procedure for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1991-07-10 | — | — | EP | disclosed |