Biphenyl

Biphenyl

SCHEMBL936183

[N-]=[N+]=[N-].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
MAPK1 P28482 2/20 0.47
TAAR1 Q96RJ0 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOTUM Q6P988 1/20 0.47
MMP3 P08254 1/20 0.47
BCL2L1 Q07817 1/20 0.47
ATM Q13315 1/20 0.43
SLC22A2 O15244 1/20 0.43
SLC22A1 O15245 1/20 0.43
SLC22A3 O75751 1/20 0.43
SLC6A4 P31645 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAOA P21397 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL31681677 1.00 ALDH1A1 (0.69) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL1775460 0.96 ALDH1A1 (0.64) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27709476 0.96 ALDH1A1 (0.64) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27722049 0.96 ALDH1A1 (0.64) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL2977612 0.96 ALDH1A1 (0.64) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL5414394 0.86 ALDH1A1 (0.60) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL936186 0.86 ALDH1A1 (0.60) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL1358618 0.83 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL30629023 0.83 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL2548048 0.83 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925614-B Small molecule probes for the discovery of active substances reactive with aldehyde groups 中山大学 2024-03-08 CN claimed
CN-116120239-A Aromatic six-membered cycloimidazole derivative, and preparation method and application thereof 沈阳药科大学 2023-05-16 CN claimed
CN-109694379-B Intermediate for preparing eribulin and preparation method thereof 江苏恒瑞医药股份有限公司 2020-09-11 CN claimed
CN-109694379-A It is used to prepare the intermediate and preparation method thereof of eribulin 江苏恒瑞医药股份有限公司 2019-04-30 CN claimed
CN-118291133-A Preparation method of pure red light perovskite quantum dot with excellent heat conduction performance 浙江大学 2024-07-05 CN disclosed
CN-118284084-A Perovskite light-emitting diode and testing method thereof 浙江大学 2024-07-02 CN disclosed
CN-118019734-A Cyclopentyl pyrazole CDK2 inhibitors 基因泰克公司 2024-05-10 CN disclosed
CN-117964573-A Dihydrobenzofuran and indene analogs as myocardial segment inhibitors 赛特凯恩蒂克公司 2024-05-03 CN disclosed
CN-117924208-A Dihydrobenzofuran and indene analogs as myocardial segment inhibitors 赛特凯恩蒂克公司 2024-04-26 CN disclosed
CN-117794527-A Novel AMP-activating protein kinase activators 学校法人京都药科大学 2024-03-29 CN disclosed
CN-117524351-A Identification method of energetic molecular framework structure 西安近代化学研究所 2024-02-06 CN disclosed
US-20230216017-A1 STRETCHABLE ELECTRODE, MANUFACTURING METHOD THEREOF, AND STRETCHABLE BATTERY COMPRISING STRETCHABLE ELECTRODE KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-07-06 US disclosed
US-6083661-A PHOTOCURABLE DIVINYLTETRAMETHYLDISILOXANE BISBENZOCYCLOBUTANE; MULTICHIP MODULES, PRINTED CIRCUITS, COATINGS THE DOW CHEMICAL COMPANY (US) 2000-07-04 US disclosed
US-6054114-A DIAGNOSING THE DEGREE OF PROGRESSION OF ALZHEIMER'S DISEASE IN A MAMMAL, MONITORING THE RESPONSE TO A THERAPY IN A MAMMAL HAVING ALZHEIMER'S DISEASE, IDENTIFYING AN AGENT USEFUL FOR TREATING ALZHEIMER'S DISEASE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-04-25 US disclosed
WO-1997041856-A9 ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO) 1998-10-01 WO disclosed
WO-1997041856-A1 ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1997-11-13 WO disclosed
US-5663306-A DISSOLVING IN SOLUTION, MIXING WITH BUFFERS FOR ACTIVE SOLUTIONS CHIRON CORPORATION (US) 1997-09-02 US disclosed
US-5585450-A PHOTODEFINABLE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-12-17 US disclosed
US-4954637-A Certain maleimide-N-alkylenecarboxylate-ortho-nitrobenzenesulfonic acid esters and derivatives useful for coupling biological materials CETUS CORPORATION (US) 1990-09-04 US disclosed
US-4943636-A PROTEINS AND PEPTIDES CETUS CORPORATION (US) 1990-07-24 US disclosed