Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272823 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL9869384 | 0.91 | — | — | |
| SCHEMBL9965402 | 0.83 | — | — | |
| SCHEMBL10284651 | 0.77 | — | — | |
| SCHEMBL22885439 | 0.77 | INMT (0.36) | MAOAMAOBDRD2DRD1DRD5 | |
| Maleic Acid SCHEMBL9877527 | 0.74 | CYP3A4 (0.45) | DRD2DRD1DRD5DRD3ADRA2A | |
| Fumaric Acid SCHEMBL9877532 | 0.74 | CYP3A4 (0.45) | DRD2DRD1DRD5DRD3ADRA2A | |
| SCHEMBL14409996 | 0.74 | KDM1A (0.38) | CYP2D6 | |
| SCHEMBL24811636 | 0.72 | CHKA (0.31) | MAOAMAOBDRD2DRD1DRD5 | |
| SCHEMBL22885428 | 0.70 | INMT (0.32) | DRD2DRD1DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418143-B1 | Dicarboxylic acids derivatives containing a nitrogen or oxygen heteroring, process for their preparation and their use as medicines | ROUSSEL UCLAF (FR) | 1994-03-23 | — | — | EP | claimed |