Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363187 | 0.93 | EPHX1 (0.55) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL2199000 | 0.87 | EPHX1 (0.72) | EPHX1ALDH1A1GAA | |
| SCHEMBL31095903 | 0.85 | EPHX1 (0.57) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL15822382 | 0.85 | EPHX1 (0.57) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL15822380 | 0.84 | EPHX1 (0.56) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL10808480 | 0.84 | ALDH1A1 (0.70) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL10808476 | 0.84 | ALDH1A1 (0.70) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL31095801 | 0.83 | EPHX1 (0.55) | EPHX1ALDH1A1GAATSHRDPP8 | |
| SCHEMBL9261105 | 0.81 | EPHX1 (0.52) | EPHX1ALDH1A1GAADPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5723839 | 0.81 | EPHX1 (0.52) | EPHX1ALDH1A1GAADPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333175-B1 | 3-Pyrrolidinylthio-1-azabicyclo (3.2.0)hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5202437-A | Bactericides, antibiotics, microbiocides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-4925838-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0333175-A1 | 3-Pyrrolidinylthio-1-azabicyclo (3.2.0)hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-20 | — | — | EP | disclosed |