Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452838 | 0.91 | TBXA2R (0.83) | TBXA2RHDAC8TBXAS1HDAC6 | |
| SCHEMBL9471812 | 0.91 | TBXA2R (0.83) | TBXA2RHDAC8 | |
| SCHEMBL9363708 | 0.88 | TBXA2R (0.60) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9363437 | 0.87 | TBXA2R (0.58) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL9364413 | 0.86 | TBXA2R (0.62) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL10357238 | 0.83 | HDAC8 (0.58) | TBXA2RHDAC8TBXAS1HDAC6 | |
| SCHEMBL9833016 | 0.82 | TBXA2R (0.65) | TBXA2RHDAC8TBXAS1 | |
| SCHEMBL10406586 | 0.80 | TBXA2R (0.65) | TBXA2R | |
| SCHEMBL10406924 | 0.80 | TBXA2R (0.65) | TBXA2R | |
| SCHEMBL10405638 | 0.80 | TBXA2R (0.65) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430459-B1 | Tetrahydronaphthalene derivatives and preparation thereof | TANABE SEIYAKU CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5206418-A | Thromboxan A2 antagonist | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5206428-A | Anticoagulants | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0430459-A1 | Tetrahydronaphthalene derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |