SCHEMBL9364251

SCHEMBL9364251

COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(OC)nc(C(F)(F)F)n1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
NPC1 O15118 2/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
SLC40A1 Q9NP59 1/20 0.40
SDHB P21912 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749899 0.92 MAPT (0.46) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL9766735 0.90 MAPT (0.56) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL7023958 0.89 NPC1 (0.50) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL9197338 0.88 MAPT (0.43) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL53993 0.88 MAPT (0.45) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL30116869 0.88 MAPT (0.45) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL29508588 0.88 MAPT (0.45) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL8857839 0.87 NPC1 (0.46) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL9363688 0.87 GAA (0.47) MAPTNPC1GAAKDM4EALDH1A1
SCHEMBL9596006 0.87 MAPT (0.43) MAPTNPC1GAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2279679-A None JP disclosed
EP-0388873-B1 [[1,3,5-Triazin-2-yl)aminocarbonyl]aminsulfonyl] benzoic acid esters as herbicides, their preparation and their use BASF AG (DE) 1994-05-11 EP disclosed
US-5071470-A Pre- or postemergence BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
JP-H02279679-A (((1,3,5-TRIAZIN-2-YL)AMINOCARBONYL)AMINOSULFONYL)BENZOIC ESTER AND HERBICIDE CONTAINING THE SAME BASF AG 1990-11-15 JP disclosed
EP-0388873-A1 [[1,3,5-Triazin-2-yl)aminocarbonyl]aminsulfonyl] benzoic acid esters as herbicides, their preparation and their use BASF Aktiengesellschaft (DE) 1990-09-26 EP disclosed