Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30068180 | 1.00 | ADORA3 (0.34) | ADORA3 | |
| SCHEMBL30921586 | 0.94 | ADORA3 (0.32) | ADORA3 | |
| SCHEMBL25169501 | 0.94 | ADORA3 (0.32) | ADORA3 | |
| SCHEMBL21834171 | 0.91 | ADORA3 (0.36) | ADORA3 | |
| SCHEMBL29752687 | 0.91 | ADORA3 (0.36) | ADORA3 | |
| SCHEMBL30954688 | 0.90 | ADORA3 (0.30) | ADORA3 | |
| SCHEMBL20469074 | 0.90 | ADORA3 (0.39) | ADORA3 | |
| SCHEMBL20991112 | 0.90 | ADORA3 (0.39) | ADORA3 | |
| SCHEMBL30574138 | 0.90 | ADORA3 (0.39) | ADORA3 | |
| SCHEMBL1743215 | 0.90 | ADORA3 (0.39) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106423281-A | Application of tris(bis(trimethylsilyl)amino)lanthanum to catalyzed preparation of spiro[cyclopropane-1,3'-indole] compound | 苏州大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-106423281-A | Application of tris(bis(trimethylsilyl)amino)lanthanum to catalyzed preparation of spiro[cyclopropane-1,3'-indole] compound | 苏州大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-0287196-B1 | Indole derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1994-11-23 | — | — | EP | disclosed |
| US-4920127-A | TREATMENT OF MIGRAINE, TRIGEMINAL NEURALGIA | BEECHAM GROUP P.L.C. (GB) | 1990-04-24 | — | — | US | disclosed |