Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039271 | 0.84 | MAPK1 (0.62) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL536696 | 0.84 | MAPK1 (0.62) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL4151771 | 0.81 | MAPK1 (0.68) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL17036528 | 0.80 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL3027838 | 0.80 | MAPK1 (0.66) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL31236317 | 0.80 | MAPK1 (0.66) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL9715941 | 0.79 | IDO1 (0.61) | IDO1 | |
| SCHEMBL9365104 | 0.79 | TDP1 (0.47) | HPGDALDH1A1LMNAIDO1POLB | |
| SCHEMBL12124412 | 0.78 | MAPK1 (0.72) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL30416948 | 0.75 | ALDH1A1 (0.72) | MAPK1TSHRHPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427484-B1 | Novel benzoxazolone compounds and the use thereof as microbicides | ROHM & HAAS (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5102898-A | Halosubstituted alkyne group; fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0427484-A1 | Novel benzoxazolone compounds and the use thereof as microbicides | ROHM AND HAAS COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |