Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501054 | 0.92 | KMT2A (0.42) | KMT2AMRGPRX1IDH2ARHTT | |
| SCHEMBL9364420 | 0.90 | CA12 (0.38) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL9500279 | 0.90 | KMT2A (0.44) | KMT2ACA12CA9MRGPRX1IDH2 | |
| SCHEMBL9499786 | 0.83 | KMT2A (0.46) | KMT2AMRGPRX1IDH2AR | |
| SCHEMBL9363379 | 0.82 | KMT2A (0.41) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL9363640 | 0.82 | SLC22A12 (0.43) | CA12CA9CA1CA2IDH2 | |
| SCHEMBL9363735 | 0.81 | KMT2A (0.46) | KMT2ACA1CA2MRGPRX1IDH2 | |
| SCHEMBL9364281 | 0.81 | MEN1 (0.43) | KMT2ACA12CA9CA1CA2 | |
| SCHEMBL9363767 | 0.81 | KMT2A (0.47) | KMT2ACA1CA2MRGPRX1IDH2 | |
| SCHEMBL9502967 | 0.80 | KMT2A (0.43) | KMT2AMRGPRX1IDH2ARHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |