Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 8/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367203 | 0.87 | MRGPRX1 (0.42) | KMT2AMRGPRX1IDH2SMN1; SMN2CCR2 | |
| SCHEMBL9323154 | 0.85 | KMT2A (0.49) | KMT2AMRGPRX1IDH2ACLYAR | |
| SCHEMBL9651520 | 0.85 | KMT2A (0.51) | KMT2AMRGPRX1ACLYMAPTSMN1; SMN2 | |
| SCHEMBL9501054 | 0.83 | KMT2A (0.42) | KMT2AMRGPRX1IDH2ACLYAR | |
| SCHEMBL9364388 | 0.83 | KMT2A (0.42) | KMT2AMRGPRX1IDH2AR | |
| SCHEMBL9499710 | 0.81 | KMT2A (0.45) | KMT2AMRGPRX1IDH2EPHX2SMN1; SMN2 | |
| SCHEMBL9500279 | 0.81 | KMT2A (0.44) | KMT2AMRGPRX1IDH2AREPHX2 | |
| SCHEMBL9653236 | 0.80 | METAP2 (0.49) | KMT2AMRGPRX1 | |
| SCHEMBL9363404 | 0.79 | KMT2A (0.42) | KMT2AMRGPRX1IDH2AREPHX2 | |
| SCHEMBL9363632 | 0.79 | KMT2A (0.49) | KMT2AMRGPRX1IDH2ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| US-5130119-A | Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |