SCHEMBL9364435

SCHEMBL9364435

CCC(=O)Nc1cc(N)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
GAA P10253 3/20 0.45
PKM P14618 1/20 0.45
HTT P42858 4/20 0.44
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
GFER P55789 2/20 0.42
HDAC1 Q13547 1/20 0.42
MAPT P10636 1/20 0.42
PRKCI P41743 1/20 0.42
RAD52 P43351 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11737601 0.98 POLB (0.45) POLBMEN1KMT2AHPGDGAA
SCHEMBL4370373 0.87 GAA (0.50) POLBMEN1KMT2AHPGDGAA
SCHEMBL27719963 0.86 HTT (0.47) POLBMEN1KMT2AGAAPKM
SCHEMBL23412892 0.84 GAA (0.55) POLBGAATDP1ALDH1A1KDM4E
SCHEMBL11689056 0.83 GAA (0.50) POLBMEN1KMT2AHPGDGAA
SCHEMBL14430163 0.82 HSP90AB1 (0.50) POLBMEN1KMT2AHPGDGAA
SCHEMBL8040847 0.80 HDAC1 (0.57) POLBMEN1KMT2AHPGDGAA
SCHEMBL12435996 0.80 RAB9A (0.43) POLBMEN1KMT2AHPGDGAA
SCHEMBL2218098 0.79 RAD52 (0.65) POLBMEN1KMT2AGAAPKM
Hydrochloric Acid SCHEMBL11734939 0.79 HDAC1 (0.56) POLBMEN1KMT2AHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345728-B1 Dye composition for keratinous fiber KAO CORP (JP) 1994-09-14 EP claimed
US-5047066-A Dye composition for keratinous fibers containing a 2-substituted 4-aminophenol compound as a developer, and a coupling substance KAO CORPORATION (JP) 1991-09-10 US claimed
EP-0345728-A2 Dye composition for keratinous fiber Kao Corporation (JP) 1989-12-13 EP claimed
EP-0345728-B1 Dye composition for keratinous fiber KAO CORP (JP) 1994-09-14 EP disclosed
US-5047066-A Dye composition for keratinous fibers containing a 2-substituted 4-aminophenol compound as a developer, and a coupling substance KAO CORPORATION (JP) 1991-09-10 US disclosed
EP-0345728-A2 Dye composition for keratinous fiber Kao Corporation (JP) 1989-12-13 EP disclosed