Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109215 | 0.98 | AKR1B1 (1.00) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| Hydrochloric Acid SCHEMBL1374156 | 0.95 | AKR1B1 (0.95) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| SCHEMBL11691926 | 0.85 | AKR1B1 (0.77) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| SCHEMBL29933615 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| SCHEMBL29570152 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL13829757 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| SCHEMBL1285811 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL3044981 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| SCHEMBL17410055 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AADRA2AADRA1AMEN1 | |
| SCHEMBL1035697 | 0.84 | AKR1B1 (0.74) | AKR1B1KMT2AADRA2AADRA1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592569-A1 | COMPOSITION AND METHOD FOR TRANSDERMAL DELIVERY OF DICLOFENAC | SANO CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0592569-A4 | COMPOSITION AND METHOD FOR TRANSDERMAL DELIVERY OF DICLOFENAC. | SANO CORP (US) | 1994-03-15 | — | — | EP | disclosed |
| WO-1993000873-A1 | COMPOSITION AND METHOD FOR TRANSDERMAL DELIVERY OF DICLOFENAC | SANO CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |