Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.57 |
| ▸ | PDE4A | P27815 | 6/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364032 | 0.93 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PDE4APDE4BPDE4C | |
| SCHEMBL9364026 | 0.93 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PDE4APDE4BPDE4C | |
| SCHEMBL9363995 | 0.86 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PDE4APDE4BPDE4C | |
| SCHEMBL9855528 | 0.85 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1HPGDKMT2A | |
| SCHEMBL9427834 | 0.84 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1 | |
| SCHEMBL9427841 | 0.84 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1 | |
| SCHEMBL9428622 | 0.84 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9364859 | 0.84 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9364855 | 0.84 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9428630 | 0.83 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403249-B1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-04-27 | — | — | EP | claimed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | claimed |
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0403249-B1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-04-27 | — | — | EP | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |