Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.38 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365208 | 0.86 | GRIA2 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9368415 | 0.82 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9364647 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9365049 | 0.80 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9080817 | 0.79 | SMN1; SMN2 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9364648 | 0.79 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9365324 | 0.78 | KDM4E (0.38) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9091900 | 0.74 | GRIA1 (0.40) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9364703 | 0.72 | KDM4E (0.35) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL9364683 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | claimed |
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |