SCHEMBL936468

SCHEMBL936468

O=C(O)CN1CCOCCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.91

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.91
KDM4E B2RXH2 3/20 0.61
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
GLA P06280 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.55
LMNA P02545 1/20 0.49
ALDH1A1 P00352 6/20 0.47
HTT P42858 2/20 0.46
USP2 O75604 2/20 0.46
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24368139 1.00 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL10567786 0.98 HSD17B10 (0.87) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL20564592 0.98 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL3873222 0.98 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL9193218 0.98 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL15935 0.98 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
Hydrochloric Acid SCHEMBL1128463 0.95 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL15572215 0.95 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL6858111 0.95 HSD17B10 (1.00) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL5762765 0.95 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036881-A Somatostatin receptor-targeting compounds and uses thereof 无锡诺宇医药科技有限公司 2026-05-15 CN claimed
WO-2026098617-A1 RADIOPHARMACEUTICAL TARGETING CARBONIC ANHYDRASE IX PROTEIN 无锡诺宇医药科技有限公司 2026-05-15 WO claimed
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS NORROY BIOSCIENCE CO LTD (CN) 2026-05-14 US claimed
EP-4696686-A1 FAPI THERANOSTIC COMPOUNDS ASSEMBLED WITH TETRAZINE LIGATION Tetrakit Technologies ApS (DK) 2026-02-18 EP claimed
EP-4696680-A1 DUAL-FUNCTIONAL TETRAZINE COMPOUNDS FOR VERSATILE RADIOLABELING WITH RADIOMETALS AND RADIOHALOGENS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS Tetrakit Technologies ApS (DK) 2026-02-18 EP claimed
US-20260007785-A1 USE OF LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), AS AGENTS FOR THE TREATMENT OF PROSTATE CANCER NOVARTIS AG (CH) 2026-01-08 US claimed
US-20260007784-A1 USE OF LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), AS AGENTS FOR THE TREATMENT OF PROSTATE CANCER NOVARTIS AG (CH) 2026-01-08 US claimed
EP-4667019-A1 PSMA-TARGETED RADIOPHARMACEUTICAL, AND SYNTHESIS AND USE THEREOF Norroy Bioscience Co., Ltd. (CN) 2025-12-24 EP claimed
WO-2025242715-A1 METHOD FOR RAPIDLY PROVIDING PYRIDAZINES FROM TETRAZINES AND CIS-DIENOPHILES TETRAKIT TECHNOLOGIES APS (DK) 2025-11-27 WO claimed
US-20250360236-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-11-27 US claimed
US-20050036947-A1 polyamino acid, wherein at least 90 percent of the amino acid residues are conjugated to signal-generating moieties attached to signal-controlling moieties via bonds that are cleavable by a physiological substance produced by the target; used in detecting and/or diagnosing of diseases; MRI GENERAL ELECTRIC COMPANY 2005-02-17 US claimed
WO-2005004992-A2 MAGNETIC RESONANCE CONTRAST-ENHANCING AGENTS AND METHOD FOR DETECTING AND IMAGING ARTHEROSCLEROTIC PLAQUE GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-01-20 WO claimed
US-20040265235-A1 Magnetic resonance contrast-enhancing agents and method for detecting and imaging artherosclerotic plaque GENERAL ELECTRIC COMPANY 2004-12-30 US claimed
US-20040022735-A1 Enzyme activated contrast agents GENERAL ELECTRIC COMPANY 2004-02-05 US claimed
JP-2833766-B2 1998-12-09 JP claimed
EP-0664819-B1 CHELATING POLYMERS NYCOMED IMAGING AS (NO) 1997-08-06 EP claimed
US-4885363-A RADIOPHARMACEUTICAL IMAGING; MEDICAL DIAGNOSIS E. R. SQUIBB & SONS, INC. (US) 1989-12-05 US claimed
WO-1989000557-A1 AMINOPOLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) 1989-01-26 WO claimed
EP-0292689-A2 Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs BRACCO INTERNATIONAL B.V. (NL) 1988-11-30 EP claimed
EP-0232751-A1 1-substituted-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs E.R. Squibb & Sons, Inc. (US) 1987-08-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS CA9, CA11, CA12 HSD17B10 205/4885KDM4E 4193/4885ALOX15 4788/4885
US-20250360236-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS KLK3, FOLH1, MPI HSD17B10 2476/4885KDM4E 3642/4885ALOX15 4151/4885
US-20260007784-A1 USE OF LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), AS AGENTS FOR THE TREATMENT OF PROSTATE CANCER KLK3, PSMA1, ACP3 HSD17B10 3549/4885KDM4E 2409/4885ALOX15 3705/4885
US-20260007785-A1 USE OF LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), AS AGENTS FOR THE TREATMENT OF PROSTATE CANCER PSMA1, ACP3, FOLH1 HSD17B10 3303/4885KDM4E 3947/4885ALOX15 2710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.