SCHEMBL15935

SCHEMBL15935

O=C(O)CN1CCOCC1

nearest known ligand 0.95

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.95
KDM4E B2RXH2 2/20 0.64
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
GLA P06280 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.57
LMNA P02545 1/20 0.50
ALDH1A1 P00352 5/20 0.49
USP2 O75604 2/20 0.47
HTT P42858 2/20 0.47
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20564592 1.00 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL3873222 1.00 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL9193218 1.00 HSD17B10 (0.95) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL5762765 0.98 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL6858111 0.98 HSD17B10 (1.00) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL24368139 0.98 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
Hydrochloric Acid SCHEMBL1128463 0.98 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL936468 0.98 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL15572215 0.98 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA
SCHEMBL2910021 0.98 HSD17B10 (0.91) HSD17B10KDM4EALOX15TSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118425362-B Organic acid metabolism marker for distinguishing wild and cultivated four-big domestic fish and application thereof 中国水产科学研究院长江水产研究所 2024-12-10 CN claimed
CN-118425362-A Organic acid metabolism marker for distinguishing wild and cultivated four-big domestic fish and application thereof 中国水产科学研究院长江水产研究所 2024-08-02 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
US-20240025949-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof TREVENA, INC. 2024-01-25 US claimed
CN-117402442-A Antibacterial PVC decorative film and preparation method thereof 黄山东仁新材料股份有限公司 2024-01-16 CN claimed
CN-114907288-B Application of nitrobenzene compounds in preparation of pseudomonas aeruginosa quorum sensing inhibitor 中国医学科学院医药生物技术研究所 2023-12-08 CN claimed
CN-117187810-A Microetching roughening solution for high-frequency high-speed circuit board and application thereof 上海天承化学有限公司 2023-12-08 CN claimed
CN-117143110-A Tumor permeation type carrier-free nano-drug and preparation method and application thereof 浙江大学 2023-12-01 CN claimed
CN-110964085-B Preparation method of carfilzomib and derivatives thereof 扬子江药业集团有限公司 2023-07-07 CN claimed
US-20220267372-A1 COMPOUNDS FOR PROTEASOME ENZYME INHIBITION ONYX PHARMACEUTICALS, INC. 2022-08-25 US claimed
CN-1302300-A Pyrrolo [1, 2-b]Pyridazine sPLA2Inhibitors SHIONOGI & CO (JP) 2001-07-04 CN claimed
EP-0730591-B1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES UPJOHN CO (US) 1999-07-14 EP claimed
US-5753652-A Antiretroviral hydrazine derivatives NOVARTIS CORPORATION (US) 1998-05-19 US claimed
US-5652238-A WATER SOLUBILITY; ANTIMICROBIAL AGENTS EFFECTIVE AGAINST RESISTANT STAPHYLOCOCCI, ENTEROCOCCI, AND STREPTOCOCCI PHARMACIA & UPJOHN COMPANY (US) 1997-07-29 US claimed
EP-0604368-B1 Anti retroviral hydrazine derivatives CIBA GEIGY AG (CH) 1996-09-18 EP claimed
EP-0730591-A1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 1996-09-11 EP claimed
WO-1995014684-A1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES THE UPJOHN COMPANY (US) 1995-06-01 WO claimed
EP-0299973-B1 ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1992-06-17 EP claimed
EP-0299973-A1 ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. UPJOHN CO (US) 1989-01-25 EP claimed
WO-1987006133-A1 ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-10-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220267372-A1 COMPOUNDS FOR PROTEASOME ENZYME INHIBITION PSMB1, PSMB9, PSMB11 HSD17B10 3937/4885KDM4E 2837/4885ALOX15 1330/4885
US-20240025949-A1 Beta-Arrestin Effectors and Compositions and Methods of Use Thereof ARRB1, FGB, SARS1 HSD17B10 3697/4885KDM4E 4840/4885ALOX15 3659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.