Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362067 | 0.99 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDCNR2KMT2A | |
| SCHEMBL9360744 | 0.98 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDCNR2KMT2A | |
| SCHEMBL9361332 | 0.93 | CYP1A2 (0.45) | ALDH1A1MAPTHPGDCNR2KMT2A | |
| SCHEMBL9366093 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDCNR2CYP1A2 | |
| SCHEMBL9361930 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCNR2CYP1A2 | |
| SCHEMBL9365846 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDCNR2CYP1A2 | |
| SCHEMBL9365112 | 0.84 | KMT2A (0.41) | ALDH1A1MAPTHPGDKMT2ACYP1A2 | |
| SCHEMBL9360901 | 0.81 | CNR2 (0.43) | ALDH1A1MAPTHPGDCNR2KMT2A | |
| SCHEMBL9361364 | 0.80 | CNR2 (0.42) | ALDH1A1MAPTHPGDCNR2KMT2A | |
| SCHEMBL9361367 | 0.80 | CYP1A2 (0.46) | ALDH1A1MAPTHPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |