Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365279 | 0.82 | SMN1; SMN2 (0.48) | HPGDCYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9369122 | 0.77 | MME (0.50) | MMEACE | |
| SCHEMBL8861625 | 0.74 | ACE (0.54) | MMEACEPOLBALDH1A1CYP2D6 | |
| SCHEMBL19326700 | 0.72 | MEN1 (0.61) | HPGDPOLBCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL19326702 | 0.72 | MEN1 (0.61) | HPGDPOLBCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL6938275 | 0.71 | CYP3A4 (0.52) | MMEHPGDPOLBCYP3A4CYP1A2 | |
| SCHEMBL1717641 | 0.70 | CYP3A4 (0.56) | HPGDCYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3099172 | 0.70 | CYP3A4 (0.56) | HPGDCYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8861615 | 0.70 | MME (0.62) | MMEHPGDACEALDH1A1CYP2D6 | |
| SCHEMBL30569656 | 0.70 | MME (0.62) | MMEHPGDACEALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | claimed |