Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717641 | 0.88 | CYP3A4 (0.56) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL6718864 | 0.85 | CYP3A4 (0.57) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL13957646 | 0.85 | CYP3A4 (0.57) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8871858 | 0.84 | CYP3A4 (0.59) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8497944 | 0.83 | CYP3A4 (0.58) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL29043644 | 0.82 | ALDH1A1 (0.54) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2733034 | 0.80 | TAAR1 (0.55) | CYP3A4ALDH1A1CYP1A2CYP2C19RAB9A | |
| SCHEMBL10576326 | 0.79 | ALDH1A1 (0.48) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL10576319 | 0.79 | ALDH1A1 (0.48) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9149607 | 0.79 | ALDH1A1 (0.50) | CYP3A4ALDH1A1CYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858934-B1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-7803887-B2 | Metallocene compounds | BASELL POLYOLEFINE GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20090221772-A1 | Bridged bis indenyl ligands where the indene ring is further fused to an oxygen or sulfur-containing ring, such as mu -{Bis-[ eta 5-8-(4-tert-butylphenyl)-6-methyl-5H-indeno[5,6-a][1,3]dioxol-5-yl]dimethylsilanediyl}dichlorozirconium; olefin polymerization catalysts; very high molecular weight | BASELL POLYLEFINE GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
| EP-1858934-A1 | METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006097500-A1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221772-A1 | Bridged bis indenyl ligands where the indene ring is further fused to an oxygen or sulfur-containing ring, such as mu -{Bis-[ eta 5-8-(4-tert-butylphenyl)-6-methyl-5H-indeno[5,6-a][1,3]dioxol-5-yl]dimethylsilanediyl}dichlorozirconium; olefin polymerization catalysts; very high molecular weight | LTC4S, HMOX1, OPRM1 | CYP3A4 723/4885ALDH1A1 2635/4885CYP1A2 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.