Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583379 | 0.73 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9365410 | 0.73 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9224956 | 0.72 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9221371 | 0.71 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9228198 | 0.71 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL9229588 | 0.71 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL9128568 | 0.70 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9128605 | 0.70 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9127208 | 0.69 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9127217 | 0.69 | ALOX5 (0.56) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375457-B1 | Cyclic ether derivatives | ICI PLC (GB) | 1994-03-16 | — | — | EP | claimed |
| EP-0375457-A2 | Cyclic ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0375457-B1 | Cyclic ether derivatives | ICI PLC (GB) | 1994-03-16 | — | — | EP | disclosed |
| US-5219881-A | Enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0375457-A2 | Cyclic ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |