Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405897 | 0.82 | SMN1; SMN2 (0.79) | SMN1; SMN2ALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL12409534 | 0.79 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28378029 | 0.79 | HDAC3 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9ASPHK2 | |
| SCHEMBL28372899 | 0.78 | DAGLA (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9ASPHK2 | |
| SCHEMBL28378370 | 0.78 | DAGLA (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9ASPHK2 | |
| SCHEMBL28373629 | 0.78 | DAGLA (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9ASPHK2 | |
| SCHEMBL10035809 | 0.78 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL13405873 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL22246722 | 0.77 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9ASPHK2 | |
| SCHEMBL5307911 | 0.76 | KDM4E (0.74) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518909-B1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AG (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0518909-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. | HOECHST AG (DE) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013941-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-19 | — | — | WO | disclosed |