Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.61 |
| ▸ | DRD2 | P14416 | 10/20 | 0.61 |
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367513 | 0.93 | HTR2A (0.61) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL9366415 | 0.89 | HTR2A (0.70) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL9366449 | 0.89 | HTR2A (0.70) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6219065 | 0.89 | HTR2A (0.70) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| Hydrochloric Acid SCHEMBL9366678 | 0.87 | HTR2A (0.68) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| Hydrochloric Acid SCHEMBL9366488 | 0.87 | HTR2A (0.68) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| Hydrochloric Acid SCHEMBL9367301 | 0.87 | HTR2A (0.68) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL9366277 | 0.85 | HTR2A (0.61) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6259705 | 0.84 | HTR2A (0.65) | HTR2ADRD2HTR1AKCNH2HTR7 | |
| SCHEMBL6261335 | 0.84 | HTR2A (0.65) | HTR2ADRD2HTR1AKCNH2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409435-B1 | Heteroaryl piperazine antipsychotic agents | PFIZER (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5350747-A | Heteroaryl piperazine antipsychotic agents | PFIZER INC (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1991000863-A1 | HETEROARYL PIPERAZINE ANTIPSYCHOTIC AGENTS | PFIZER INC. (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0409435-A1 | Heteroaryl piperazine antipsychotic agents | PFIZER INC. (US) | 1991-01-23 | — | — | EP | disclosed |