Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 5/20 | 0.47 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321666 | 0.81 | TYMS (0.57) | HSD17B10KDM4ELMNATYMSIP6K1 | |
| SCHEMBL7257451 | 0.78 | KDM4E (0.59) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL9514599 | 0.78 | KDM4E (0.59) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL27812566 | 0.74 | KDM4E (0.55) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL27496027 | 0.74 | KDM4E (0.55) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL9555707 | 0.72 | KDM4E (0.52) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL29901695 | 0.71 | KDM4E (0.62) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL28637729 | 0.71 | KDM4E (0.62) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL29535139 | 0.71 | KDM4E (0.66) | HSD17B10KDM4ELMNAPOLBNPSR1 | |
| SCHEMBL7263029 | 0.71 | KDM4E (0.66) | HSD17B10KDM4ELMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373891-B1 | Anti-tumour agents | ICI PLC (GB) | 1994-11-02 | — | — | EP | disclosed |