Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531547 | 0.88 | APOBEC3A (0.56) | BCHEACHEAPOBEC3AAPOBEC3GHTR1A | |
| SCHEMBL27580688 | 0.80 | BCHE (0.42) | BCHEACHEAPOBEC3AAPOBEC3GHTR1A | |
| SCHEMBL21957767 | 0.79 | BCHE (0.41) | BCHEACHEHTR1AMAOASLC6A2 | |
| Acetamide SCHEMBL27397023 | 0.78 | ACHE (0.53) | BCHEACHEAPOBEC3AAPOBEC3GHTR1A | |
| SCHEMBL22188512 | 0.78 | ACHE (0.41) | BCHEACHELMNANPSR1ALDH1A1 | |
| SCHEMBL2811793 | 0.78 | ACHE (0.50) | BCHEACHEAPOBEC3AAPOBEC3GHTR1A | |
| Dodecane SCHEMBL27419560 | 0.77 | BCHE (0.46) | BCHEACHEAPOBEC3AAPOBEC3GHTR1A | |
| SCHEMBL1684199 | 0.76 | APOBEC3A (0.61) | ACHEAPOBEC3AAPOBEC3GLMNAALDH1A1 | |
| SCHEMBL12020265 | 0.76 | APOBEC3A (0.61) | ACHEAPOBEC3AAPOBEC3GLMNAALDH1A1 | |
| SCHEMBL7639305 | 0.75 | APOBEC3A (0.48) | ACHEAPOBEC3AAPOBEC3GLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147621-A | Amine stabilizer | CHEMIE AG BITTERFELD-WOLFEN (DE) | 1992-09-15 | — | — | US | claimed |
| EP-0499650-B1 | Method for stabilization of phosphorus trichloride | BITTERFELD WOLFEN CHEMIE (DE) | 1994-08-24 | — | — | EP | disclosed |
| US-5147621-A | Amine stabilizer | CHEMIE AG BITTERFELD-WOLFEN (DE) | 1992-09-15 | — | — | US | disclosed |
| EP-0499650-A1 | Method for stabilization of phosphorus trichloride | Akzo Nobel N.V. (NL) | 1992-08-26 | — | — | EP | disclosed |